Ribostamycin sulfate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Ribostamycin 是一种广谱抗菌剂，在 30S 和 50S 核糖体亚基结合水平抑制细菌蛋白质合成，还抑制蛋白质二硫键异构酶 (PDI) 的伴侣活性，用于药代动力学和肾毒性研究。

Ribostamycin is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies.(In Vitro):Ribostamycin is as an intermediate in the biosynthesis of neomycin.Ribostamycin inhibited the chaperone activity of protein disulfide isomerase (PDI), but it did not inhibit the isomerase activity.Ribostamycin is effective against both gram-positive and gram-negative cocci and bacilli including drug-resistant strains. Ribostamycin is especially effective against the gentamicin-resistant bacterium Klebsiella pneumoniae, which possesses aminoglycoside-modifying enzymes.

Ribostamycin is as an intermediate in the biosynthesis of neomycin.Ribostamycin inhibited the chaperone activity of protein disulfide isomerase (PDI), but it did not inhibit the isomerase activity.Ribostamycin is effective against both gram-positive and gram-negative cocci and bacilli including drug-resistant strains. Ribostamycin is especially effective against the gentamicin-resistant bacterium Klebsiella pneumoniae, which possesses aminoglycoside-modifying enzymes.

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Others

Other Targets

Others

Infection

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53797-35-6

552.55

C17H34N4O10·H2SO4

>98% (HPLC)

Water: 100 mg/mL (180.97 mM)

C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O)N.OS(=O)(=O)O

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(-20℃)

With Ice Pack

≥ 2 years